abstract：RATIONALE AND OBJECTIVES:The authors investigate whether a modified gadolinium (Gd)-DTPA formulation can be aerosolized and used as a contrast agent for magnetic resonance (MR) ventilation imaging of the lungs. METHODS:Gadolinium-DTPA (gadopentetate dimeglumine, Schering AG, Berlin, Germany, 100 mmol Gd/L) was modifie...

journal_title：Investigative radiology

authors： Misselwitz B,Mühler A,Heinzelmann I,Böck JC,Weinmann HJ

更新日期：1997-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...

journal_title：Investigative radiology

authors： Casali C,Obadia JF,Canet E,Bendjelid K,André-Fouët X,Revel D,Janier MF

更新日期：1997-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors determine the relative effect of soft-tissue compartments, body fat (percent [%Bfat] and weight [Bfat kg]) and fat-free mass (FFM kg), on measurements of ultrasound bone velocity (UBV m/second). METHODS:The authors measured UBV in proximal phalanxes and body fat and fat-free mass b...

journal_title：Investigative radiology

authors： Gómez M,Aguado F,Manuel J,Menéndez JM,Revilla M,Villa LF,Cortés J,Rico H

更新日期：1997-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The clinically most widely used devices (Porstmann-plug, Rashkind-umbrella, Botallooccluder) have inherent specific limitations (eg, transarterial approach, residual shunts, limited retrieval). The authors assess practicability, efficacy, and tissue reaction of the new retrievable transvenous p...

journal_title：Investigative radiology

authors： Grabitz RG,Schräder R,Sigler M,Seghaye MC,Dzionsko C,Handt S,Schneidt B,Von Bernuth G

更新日期：1997-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors developed a two-dimensional breathhold magnetic resonance (MR) technique for the direct imaging of pulmonary emboli. METHODS:In vitro MR imaging was performed to demonstrate the potential generation of clot-blood contrast by in vivo pulmonary embolism (PE). A two-dimensional magnet...

journal_title：Investigative radiology

authors： Moody AR,Liddicoat A,Krarup K

更新日期：1997-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors evaluate the use of magnetic resonance (MR) to image pulmonary perfusion in healthy controls and to detect pulmonary defects in patients with unilateral lung transplantation, using dynamic images after contrast administration. METHODS:Five patients with right lung transplantation a...

journal_title：Investigative radiology

authors： Berthezène Y,Croisille P,Bertocchi M,Houzard C,Bendib K,Revel D

更新日期：1997-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors detect activation in the auditory cortex during cochlear electrical stimulation in deaf patients using functional magnetic resonance (MR) imaging. METHODS:Stimulating electrode was inserted gently under local anesthesia close to the round window membrane of the cochlea in seven coc...

journal_title：Investigative radiology

authors： Berthezène Y,Truy E,Morgon A,Giard MH,Hermier M,Franconi JM,Froment JC

更新日期：1997-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors conduct technical feasibility and performance studies on a new 0.009-inch nitinol microguidewire for potential neuroendovascular applications. METHODS:In vivo microcatheterizations of brachiocephalic arteries were performed in four pigs using the 0.009-inch nitinol microguidewire w...

journal_title：Investigative radiology

authors： Putman CM,Chaloupka JC,Kailasnath P,Alderman J

更新日期：1997-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the incidence and distribution of orthopedic injuries sustained in Operation Desert Shield and Desert Storm by evaluating whether existing diagnostic imaging modalities were sufficient to diagnose the types of musculoskeletal injuries incurred. The authors also sought to det...

journal_title：Investigative radiology

authors： Truax AL,Chandnani VP,Chacko AK,Gonzalez DM

更新日期：1997-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria. METHODS:The device consists of a symmetrical cage of six superelastic monofile wires, including a mic...

journal_title：Investigative radiology

authors： Grabitz RG,Handt S,Vanopbroeke HJ,Seghaye MC,Franke A,Osypka P,von Bernuth G

更新日期：1997-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied premenopausal, perimenopausal, and postmenopausal women to determine if ultrasound bone velocity (UBV) on proximal phalanges of women reflect bone changes related to gonadal status and age. METHODS:A total of 166 healthy women-64 postmenopausal women (mean age 58.7 +/- 9.4 ...

journal_title：Investigative radiology

authors： Aguado F,Revilla M,Hernández ER,Villa LF,Rico H

更新日期：1997-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To analyze changes in Doppler ultrasound variables of the portal vein in relation to liver biopsy findings, the authors performed a prospective study of 316 Doppler ultrasound examinations in the first 2 weeks after orthotopic liver transplantation on 23 patients. METHODS:Recordings were obtai...

journal_title：Investigative radiology

authors： Kok T,Slooff MJ,Peeters PM,Zwaveling JH,Bijleveld CM,Gi-van Loon CE,Klompmaker IJ,Haagsma EB

更新日期：1996-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study evaluated the value of dynamically enhanced fast low-angle shot (FLASH) magnetic resonance (MR) imaging in measuring cardiac output with and without dipyridamole pharmacological stress. METHODS:Ten subjects underwent rest and stress MR imaging. Rest images were acquired using electr...

journal_title：Investigative radiology

authors： Tello R,Hartnell GG,Hill TC,Cerel A,Finn JP,Kamalesh M,Cohen M,Lewis S

更新日期：1996-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The relative stability and selectivity of magnetic resonance (MR) imaging contrast agents were compared with in vitro transmetallation and ligand competition reactions. MATERIALS AND METHODS:A gadolinium (Gd)-DTPA-BIGA, Gd-DTPA-BMA, Gd-DTPA, or Gd-HP-DO3A solution was mixed with an equimolar s...

journal_title：Investigative radiology

authors： Puttagunta NR,Gibby WA,Puttagunta VL

更新日期：1996-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:The authors performed a retrospective study in ultrasound to investigate new aspects in the sonomorphology of lymph node metastases of the neck. In this study, it could be demonstrated the first time that the histologic characteristics of the metastases determine the sonographic appearance. In a...

journal_title：Investigative radiology

authors： Mäurer J,Willam C,Steinkamp HJ,Knollmann FD,Felix R

更新日期：1996-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The ventral sacroiliac ligament (VSL), which bridges the sacroiliac (SI) joint anteriorly, has been described as an important stabilizing structure of the joint, but no data exist regarding its assessment with routine and advanced imaging methods. The authors determine the imaging appearance of...

journal_title：Investigative radiology

authors： Jaovisidha S,Ryu KN,De Maeseneer M,Haghighi P,Goodwin D,Sartoris DJ,Resnick D

更新日期：1996-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors differentiate breast lesions on sonography by measurements in two compression states that are perpendicular to each other. METHODS:Diameters of 100 breast lesions were measured preoperatively under lateromedial and craniocaudal compression with a new sonographic method. This method...

journal_title：Investigative radiology

authors： Richter K,Willrodt RG,Opri F,Heywang-Köbrunner SH

更新日期：1996-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors differentiate acute tubular necrosis from transplant rejection in patients with delayed kidney graft function using gadolinium (Gd)-DTPA enhanced magnetic resonance (MR) imaging. METHODS:Twenty-four patients after renal transplantation (10 with normal graft function, 14 with delaye...

journal_title：Investigative radiology

authors： Preidler KW,Szolar D,Schreyer H,Ebner F,Kern R,Holzer H,Horina JH

更新日期：1996-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The author analyzes findings of consistency of rotator-cuff calcifications found at ultrasound (US)-guided needle treatment compared with findings of plain radiography, US, and computed tomography (CT). METHODS:Twenty patients had rotator-cuff calcifications (mean diameter, 1.5 cm; range, 1.1-...

journal_title：Investigative radiology

authors： Farin PU

更新日期：1996-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...

journal_title：Investigative radiology

authors： Benness G,Khangure M,Morris I,Warwick A,Burrows P,Vogler H,Weinmann HJ

更新日期：1996-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the role of granulocytes in reperfusion injury after liver transplantation. The authors injected radiolabeled granulocytes to determine if human liver graft outcome could be correlated with granulocyte accumulation. MATERIALS AND METHODS:Pure granulocyte suspension was prepared fro...

journal_title：Investigative radiology

authors： Ziser A,Forstrom LA,Plevak DJ,Sanchez-Urdazpal L,Gores GJ,Wiesner RH,Batts KP,Krom RA

更新日期：1996-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of the study was to evaluate the effect of articular fluid distention on patellar position at different degrees of knee angulation. METHODS:Patellar position in 10 cadaveric knee specimens was determined with 30, 100, and 200 mm Hg joint distention at 45, 20, and 5 degrees of knee ...

journal_title：Investigative radiology

authors： Brossmann J,Koch S,Schwarzenberg H,Link J,Muhle C,Bull CC,Heller M

更新日期：1996-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:A new hepatobiliary gadolinium chelate, gadolinium (Gd) 2,5-BPA-DO3A, was compared in two animal species with Gd HP-DO3A (gadoteridol), a clinically approved extracellular contrast agent, and Gd Cy2-DOTA, a second hepatobiliary chelate in preclinical development. The ligand in Gd 2,5-BPA-DO3A i...

journal_title：Investigative radiology

authors： Runge VM,Wells JW,Williams NM

更新日期：1996-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Target-specific magnetic resonance (MR) contrast agents are being developed to improve the accuracy of MR imaging. The purpose of this study was to determine the mechanism of cell uptake, and modes of intracellular trafficking of a prototypical iron oxide label (RMA) used in the synthesis of so...

journal_title：Investigative radiology

authors： Schulze E,Ferrucci JT Jr,Poss K,Lapointe L,Bogdanova A,Weissleder R

更新日期：1995-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the efficacy of oral administration of cilostazol, an antithrombotic agent, for the prevention of thrombotic occlusion and intimal hyperplasia after stenting. METHODS:Single-bodied Z-stents were placed in the iliac arteries of 23 dogs. Before stenting, an embolizing coil was introd...

journal_title：Investigative radiology

authors： Kubota Y,Kichikawa K,Uchida H,Maeda M,Nishimine K,Makutani S,Sakaguchi S,Yoshioka T,Ohishi H,Kimura Y

更新日期：1995-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The basic characteristics of BR1, a novel echo contrast agent based on stabilized sulfur hexafluoride (SF6) microbubbles have been evaluated. METHODS:The authors determined the physicochemical properties (bubble concentration, bubble size distribution, resistance to pressure, and stability) an...

journal_title：Investigative radiology

authors： Schneider M,Arditi M,Barrau MB,Brochot J,Broillet A,Ventrone R,Yan F

更新日期：1995-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare technical aspects and neointima formation of a new Nitinol stent and a Wallstent. METHODS:A Nitinol sten and a Wallstent were placed into the iliac arteries of 14 sheep (total of 28 stents) and followed angiographically. Seven sheep were killed after 1 month and 7 after 4.5 months. ...

journal_title：Investigative radiology

authors： Schürmann K,Vorwerk D,Kulisch A,Stroehmer-Kulisch E,Biesterfeld S,Stopinski T,Günther RW

更新日期：1995-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the long-term distribution of gadolinium (Gd) in mice and rats after the administration of four commercially available magnetic resonance imaging contrast media. The goals were to determine any possible product dissociation in vivo and to evaluate the effects that product ex...

journal_title：Investigative radiology

authors： Tweedle MF,Wedeking P,Kumar K

更新日期：1995-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To investigate postmortem metabolic and morphologic alterations in the dog brain thalamus and to contribute diagnostic aids in medicolegal science. METHODS:A homogeneous group of 17 dogs was used for in vivo 1H magnetic resonance (MR) spectroscopy and electron microscopic studies, which were p...

journal_title：Investigative radiology

authors： Choe BY,Gil HJ,Suh TS,Shinn KS

更新日期：1995-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Optimal dose schedules and total dose of ionizing radiation for human central nervous system malignancy are not known. An animal model has been developed for the investigation of rat central nervous system response to proton irradiation using magnetic resonance imaging (MRI). A clinical MRI dev...

journal_title：Investigative radiology

authors： Kennedy AS,Archambeau JO,Archambeau MH,Holshouser B,Thompson J,Moyers M,Hinshaw D Jr,Slater JM

更新日期：1995-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the effect of contrast dose, use of magnetization transfer (MT), and temporal delay on the visualization of contrast enhancement with gadoteridol (Gd HP-DO3A) in a canine brain abscess model. METHODS:Alpha streptococcus brain abscesses were studied in five dogs at 1.5 tesla...

journal_title：Investigative radiology

authors： Runge VM,Wells JW,Kirsch JE

更新日期：1995-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gd-DTPA is a well-characterized, safe contrast agent frequently used in magnetic resonance imaging (MRI) of the central nervous system. The purpose of this double-blind, comparative MRI study of brain, spine, trunk, and limbs was to evaluate the safety and efficacy of Gd-DOTA versus Gd-DTPA in ...

journal_title：Investigative radiology

authors： Oudkerk M,Sijens PE,Van Beek EJ,Kuijpers TJ

更新日期：1995-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Bolus injection of iodinated contrast media has been observed to alter myocardial mechanical function, but the consequences on cellular metabolism are poorly documented. Modifications of metabolic parameters (intracellular pH as well as adenosine triphosphate [ATP], phosphocreatine, and inorgan...

journal_title：Investigative radiology

authors： Goossens A,Vander Elst L,Van Haverbeke Y,Muller RN

更新日期：1995-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To study cellular mechanisms that cause contrast media nephropathy, an in vitro system for proximal and distal tubular cells has been established to evaluate the influence of x-ray contrast media on tubular function. METHODS:Confluent cell cultures of the two renal cell lines, proximal tubule ...

journal_title：Investigative radiology

authors： Andersen KJ,Christensen EI,Vik H

更新日期：1994-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Two independent gold standards and diagnoses from three-dimensional computed tomography (CT) images were used to examine the possibility that craniosynostosis is a binary abnormality that potentially may be diagnosed without error. METHODS:Surgical reports, histology of excised sutures, and th...

journal_title：Investigative radiology

authors： Pilgram TK,Vannier MW,Marsh JL,Kraemer BB,Rayne SC,Gado MH,Moran CJ,McAlister WH,Shackelford GD,Hardesty RA

更新日期：1994-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Magnetic resonance microscopy (MRM) has evolved from a technical curiosity to a tool with which researchers can study important disease models. But MRM is not simply an extension of clinical magnetic resonance imaging. In this article, the unique adaptations of MRM required in the study of caro...

journal_title：Investigative radiology

authors： Arnder L,Zhou X,Cofer GP,Hedlund LW,Johnson GA

更新日期：1994-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Low-field magnetic resonance imaging (MRI) evaluation of breast implants is described, with emphasis on the capabilities provided by different imaging sequences. METHODS:Open architecture MR images using a .064-T permanent magnet and three-dimensional Fourier transform and inversion recovery s...

journal_title：Investigative radiology

authors： Frankel S,Occhipinti K,Kaufman L,Kramer D,Carlson J,Mineyev M,Friedenthal R

更新日期：1994-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:This study was devised to develop a method of measuring the acute effects of radiocontrast media on renal function and assessing the relationship of the dose of radiocontrast media infused with the incidence of radiocontrast-induced renal failure. In addition, the drug adenosine phosphate-magne...

journal_title：Investigative radiology

authors： Albert SG,Shapiro MJ,Brown WW,Goodgold H,Zuckerman D,Durham R,Kern M,Fletcher J,Wolverson M,Plummer ES

更新日期：1994-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Iopromide is a new monomeric, nonionic contrast agent that exhibits low osmolality and low viscosity in high concentration in aqueous solutions. Double-blind, randomized clinical trials have established the efficacy, safety, and tolerance of iopromide for excretory urography, coronary angiograp...

journal_title：Investigative radiology

authors： Goldberg SN,Abrahams J,Drayer BP,Golding S,Bernardino M,Brunetti J

更新日期：1994-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Indium-111 (111In)-labeled leukocyte scanning has been used frequently in patients suspected of having infections. Recently, technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) has been used to label leukocytes. This study was undertaken to determine the distribution and dosimetry of 9...

journal_title：Investigative radiology

authors： Brown ML,Hung JC,Vetter RJ,O'Connor MK,Chowdhury S,Forstrom LA

更新日期：1994-04-01 00:00:00